CoxMDS: multiple data splitting for high-dimensional mediation analysis with survival outcomes in epigenome-wide studies

CoxMDS is a multiple data splitting framework for high-dimensional mediation analysis with survival outcomes. The method is designed to identify potential mediators while providing finite-sample false discovery rate control, including settings with correlated or non-Gaussian mediators.

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Recommended citation: Yao, M., Tian, P.*, Li, X., et al. (2026). "CoxMDS: multiple data splitting for high-dimensional mediation analysis with survival outcomes in epigenome-wide studies." Briefings in Bioinformatics, 27(1), bbaf730.
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